HCID 19819017, compound → HCID 19819020, compound

HRID 1195238Notes

Reaction equation

HRID 1195238 reaction equation
[ClH:1].[CH:2]1([C:5]([CH:7]2[CH2:9][CH2:8]2)=[NH:6])[CH2:4][CH2:3]1>CS(C)=O>[Cl-:1].[N+:6]12[CH2:9][CH2:8][CH2:7][C:5]=1[CH2:2][CH2:3][CH2:4]2

Participants

3

Reactant 1

HCID 19819017HCID 19819017, compound

Product 1

HCID 19819020HCID 19819020, compoundYield 55%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
100 °C

Procedure

A solution of dicyclopropylmethanimine hydrochloride (1.00 g, 6.87 mmol) in 6.0 ml of dimethyl sulfoxide was heated with stirring at 100° C. for 4 hours. The solvent was distilled out in vacuo and isobutyl alcohol (6 ml) was added to the residue. Precipitated crystals was obtained and dried in vacuo to afford 0.55 g (Yield: 55%) of the desired compound.

Workup

  1. distillationThe solvent was distilled out in vacuo and isobutyl alcohol (6 ml)
  2. additionwas added to the residue
  3. customPrecipitated crystals
  4. customwas obtained
  5. customdried in vacuo

Sources & evidence

ORD record
ord-d0db1dab158242feb1f62fa127826663
Source dataset
uspto-grants-1992_05
Patent number
US05110945

Reaction notes

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