Dimethylamine → HCID 53887279, compound

Participants

Reaction Steps

In a manner analogous to that described in Example 2 it is possible, by reacting 2-chloro-9-(2,6-difluorobenzyl)-6-(N-methylamino)-9H-purine (Example 17) with N,N-dimethylamine, to obtain the 9-(2,6-difluorobenzyl)-2-(N,N-dimethylamino)-6-(N-methylamino)-9H-purine, which has a melting range of from 196° to 199° (methanol), the reaction mixture being heated at 140° for 24 hours.

Provenance & Evidence