Methylamine → HCID 53856434, compound

HRID 1195441Notes

Reaction equation

HRID 1195441 reaction equation
Cl[C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])=[C:4]([NH:19][CH3:20])[N:3]=1.[CH3:21][NH2:22]>>[CH3:21][NH:22][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])=[C:4]([NH:19][CH3:20])[N:3]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 54051665HCID 54051665, compound

Product 1

HCID 53856434HCID 53856434, compound

Procedure

In a manner analogous to that described in Example 2 it is possible, by reacting 2-chloro-9-(2-chlorobenzyl)-6-(N-methylamino)-9H-purine (Example 18) with N-methylamine, to obtain the 2,6-bis(N-methylamino)-9-(2-chlorobenzyl)-9H-purine, which has a melting range of from 151° to 152°, the reaction mixture being heated at 120° for 20 hours.

Sources & evidence

ORD record
ord-d46c9f62f7d1408fbc842d9ffd275302
Source dataset
uspto-grants-1992_05
Patent number
US05110818

Reaction notes

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