Hydrofluoric Acid → 2-(4-Methylphenyl)-2-[4-(4-methylphenoxy)phenyl]hexafluoropropane

HRID 1195445Notes

Reaction equation

HRID 1195445 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)([C:13]([F:16])([F:15])[F:14])[C:9]([F:12])([F:11])[F:10])=[CH:4][CH:3]=1.[CH3:24][C:25]1[CH:30]=[CH:29][C:28](OC2C=CC=CC=2)=[CH:27][CH:26]=1.F>>[CH3:23][C:20]1[CH:19]=[CH:18][C:17]([C:8]([C:5]2[CH:6]=[CH:7][C:2]([O:1][C:28]3[CH:29]=[CH:30][C:25]([CH3:24])=[CH:26][CH:27]=3)=[CH:3][CH:4]=2)([C:9]([F:10])([F:11])[F:12])[C:13]([F:14])([F:15])[F:16])=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 14917Hydrofluoric AcidHCID 74351p-PhenoxytolueneHCID 148323252-(4-Hydroxyphenyl)-2-(4-methylphenyl)hexafluoropropane

Product 1

HCID 148323262-(4-Methylphenyl)-2-[4-(4-methylphenoxy)phenyl]hexafluoropropane

Procedure

reacting 2-(4-hydroxyphenyl)-2-(4-methylphenyl)hexafluoropropane with an aromatic, halogen-containing nitro compound or dinitro compound, or reacting 2-(4-methylphenyl)-2-hexafluoroisopropanol with 4-methyldiphenyl ether in the presence of anhydrous hydrofluoric acid to give 2-(4-methylphenyl)-2-[4-(4-methylphenoxy)phenyl]hexafluoropropane,

Sources & evidence

ORD record
ord-6f6d597e489e4ad3a57e692ab16a30c2
Source dataset
uspto-grants-1992_05
Patent number
US05110983

Reaction notes

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