1,2-Dichloroethane → HCID 19819138, compound

Participants

Reaction Steps

β-Chloropropionyl chloride (71.9 g, 566 mmole) was added to a mixture of aluminium chloride (75.5 g, 566 mmole) and ethylene dichloride (200 ml). To this mixture was added p-xylene (60.0 g, 566 mmole) and the solution was stirred at room temperature for 30 minutes, then poured into dilute hydrochloric acid. The organic layer was separated, washed with water and dried over anhydrous sodium sulfate. Evaporation of the solvent under reduced pressure gave 2-(2-chloropropionyl)-2,4-dimethylbenzene a yellowish oil, which was used immediately in the next step of the sequence.

Provenance & Evidence