Methyl bromoacetate → HCID 15166964, compound

HRID 1195651Notes

Reaction equation

HRID 1195651 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([OH:16])=[CH:5][C:6]([C:12]([O:14][CH3:15])=[O:13])=[N:7]2.Br[CH2:18][C:19]([O:21][CH3:22])=[O:20]>>[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([O:16][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:5][C:6]([C:12]([O:14][CH3:15])=[O:13])=[N:7]2

Participants

3

Reactant 2

HCID 60984Methyl bromoacetateHCID 178498515HCID 178498515, compound

Product 1

HCID 15166964HCID 15166964, compound

Procedure

The purified methyl 5-chloro-4-hydroxy-2-quinoline-carboxylate is alkylated with methyl bromoacetate as described in example 2 to produce methyl 5-chloro-4-methoxycarbonylmethyloxy-2-quinolinecarboxylate.

Sources & evidence

ORD record
ord-442ff6602f334366bb4f7cedf2467823
Source dataset
uspto-grants-1992_05
Patent number
US05112821

Reaction notes

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