反应详情

Ethyl [(9-amino-1,2,3,4-tetrahydroacridin-8-yl)oxy]acetate (14.50 g) was dissolved in dry tetrahydrofuran (350 ml) and potassium t-butoxide (6.0 g) was added. After stirring for 1 hr, 100 ml saturated ammonium chloride solution (100 ml) was added, and stirring was continued for 30 min. The reaction mixture was evaporated under reduced pressure. The solid was collected and washed with water to give 10.15 g (82.65%) of product, mp 201°-202° C.

1. stirringstirring
2. waitwas continued for 30 min
3. customThe reaction mixture was evaporated under reduced pressure
4. customThe solid was collected
5. washwashed with water