HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 53945931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 12252137 | HCID 12252137 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 53945931 | HCID 53945931 | — |
Reaction Steps
2 g of 1-Phenyl-1-tolylethanol are stirred overnight with 0.56 g of 80% NaH in 50 ml of tetrahydrofuran, 3.7 g of methyliodide added and stirring continued for 6 hours. The mixture is worked up with aq. HCl, extracted with dichloromethane and the oily product purified over a silica gel column with cyclohexane as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112851 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-867d1899a54249deb48caf5a0fbfbc53 |
| Source note | uspto-grants-1992_05 |