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HRID1195871

反应详情

EQUATION

反应方程式

HRID 1195871 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl
HCID4037

Meclofenamic acid

C14H11Cl2NO2

结构：O=C(Cl)C(=O)Cl
HCID65578

Ethanedioyl dichloride

C2Cl2O2

PRODUCTS

生成物

1
结构：COC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl
HCID76743

Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, methyl ester

C15H13Cl2NO2

收率 89%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid is reacted with oxalyl chloride and methanol according to the procedure of Example 25 to give 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid, methyl ester in 89% yield; mp 132°-134° C.