HCID 86438, compound → HCID 54473635, compound

HRID 1195903Notes

Reaction equation

HRID 1195903 reaction equation
COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:10])=CC=1.[CH3:23][O:24][N:25]=[C:26]([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=1[CH2:37][O:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][C:40]=1[CH3:45])[C:27]([O:29][CH3:30])=O>C1(C)C(C)=CC=CC=1>[CH3:23][O:24][N:25]=[C:26]([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=1[CH2:37][O:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][C:40]=1[CH3:45])[C:27]([O:29][CH3:30])=[S:10]

Participants

4

Reactant 2

HCID 86438HCID 86438, compoundHCID 87949Lawesson's reagent

Product 1

HCID 54473635HCID 54473635, compoundYield 59%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

16.6 g (41 mmol) of Lawesson's reagent were added to 10.2 g (33 mmol) of 2-[2-methylphenoxymethyl]-phenylglyoxylic acid methyl ester O-methyloxime in 50 ml of xylene. Refluxing was carried out for 24 hours and the solvent was removed under reduced pressure. Chromatography over silica gel using ethyl acetate/hexane gave 6.3 g (59%) of the compound as a black oil.

Workup

  1. temperatureRefluxing
  2. customthe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-5b35c6664e5e4ebd8d82f2b7d989a525
Source dataset
uspto-grants-1992_05
Patent number
US05112860

Reaction notes

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