Hydrochloric Acid → HCID 226318, compound

HRID 1195930Notes

Reaction equation

HRID 1195930 reaction equation
[N+:1]([C:4]1[C:5]([OH:14])=[C:6]([O:12][CH3:13])[CH:7]=[C:8]([CH:11]=1)[CH:9]=O)([O-:3])=[O:2].C(O)(=O)[CH2:16][C:17]([OH:19])=[O:18].Cl>N1C=CC=CC=1.O>[OH:14][C:5]1[C:4]([N+:1]([O-:3])=[O:2])=[CH:11][C:8]([CH:9]=[CH:16][C:17]([OH:19])=[O:18])=[CH:7][C:6]=1[O:12][CH3:13]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 867Malonic AcidHCID 811345-Nitrovanillin

Product 1

HCID 226318HCID 226318, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 1049PyridineSolvent

Procedure

A solution of 1.0 g of 5-nitrovanillin and 4.0 g of malonic acid in 10 ml of pyridine was heated for 50 h at 80° C. The reaction mixture was diluted with water, acidified with hydrochloric acid, filtered, washed with water and dried. Yield 0.44 g (36%). The 1H-NMR spectrum was in accordance with the structure alleged.

Workup

  1. filtrationfiltered
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-4eaf70c168a845718102ad9c7ad9e431
Source dataset
uspto-grants-1992_05
Patent number
US05112861

Reaction notes

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