Methyl Acrylate → HCID 54378182, compound

HRID 1196050Notes

Reaction equation

HRID 1196050 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH:4]=[CH2:5].[NH2:7][CH2:8][CH2:9][CH:10]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[O:12][C:11]1([CH3:21])[CH3:20]>CO>[CH3:20][C:11]1([CH3:21])[CH:10]([CH2:9][CH2:8][N:7]([CH2:5][CH2:4][C:3]([O:2][CH3:1])=[O:6])[CH2:5][CH2:4][C:3]([O:2][CH3:1])=[O:6])[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[O:12]1

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 53697549HCID 53697549, compound

Product 1

HCID 54378182HCID 54378182, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4.74 g (55 mmol) of acrylic acid methyl ester are added at room temperature to a solution of 5.13 g (25 mmol) of 3-(2-aminoethyl)-2,2-dimethyl-chroman in 50 ml of methanol. The mixture is stirred for 16 hours at room temperature and then concentrated by evaporation in vacuo, yielding 9.43 g (100% of the theoretical yield) of N-[2-(2,2-dimethylchroman-3-yl)-ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine in the form of a light-yellow oil which is further used in that form.

Workup

  1. concentrationconcentrated by evaporation in vacuo
  2. customyielding 9.43 g (100% of the

Sources & evidence

ORD record
ord-10dc0042972548ca8d5acd9d3c9edf90
Source dataset
uspto-grants-1992_05
Patent number
US05112855

Reaction notes

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