Hydrochloric Acid → HCID 67831434, compound

Participants

Reaction Steps

The same esterification procedure as in Example 1 was followed with the exception that 165.2 g of L-phenylalanine and 165.2 g of methanol were used and that hydrochloric acid was replaced with 132.1 g of 89% phosphoric acid. The reaction was conducted at 60 ° C. for 8 hours, followed by cooling in order to deposit the crystals, which were collected by filtration and then dried to obtain 169.4 g (58.1% yield) of L-phenylalanine methyl ester phosphate having a purity of 95.1% and containing 0.3% of water and 3.0% of L-phenylalanine.

Provenance & Evidence