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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1196302Generated: October 26, 2026

4-Methylmorpholine → HCID 178512170, compound

https://huagongshe.com/reaction/1196302

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylmorpholineHCID 7972—
Reactant1,2-Pyrrolidinedicarboxylic acid, 2-(2,5-dioxo-1-pyrrolidinyl) 1-(phenylmethyl) ester, (2S)-HCID 853482—
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ReactantHCID 178454213HCID 178454213—
ProductHCID 178512170HCID 178512170—

Reaction Steps

The desired compound was prepared from 0.68 g of Boc-Asn-Ser(Bzl)-Pip-Arg(NO2)-OBzl, 3 ml of 4N HCl-AcOEt, 0.14 ml of NMM and 0.32 g of Z-Pro-OSu in the same manner as in Example 12-(2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05112947
Source datasetuspto-grants-1992_05
ORD IDord-d99cea40701d42eea0cbb008eb9e263c
Source noteuspto-grants-1992_05