反应详情

6-(Carbethoxymethyl)-3-phenyl-2-cyclohexen-1-one (2.11 g) was added to a mixture of 0.2 g of 10% palladium on carbon in 30 ml of ethyl acetate. The reaction mixture was hydrogenated under a hydrogen atmosphere (maximum pressure 45 psi) for 41 hours. The mixture was filtered through celite, and the solvent was removed under reduced pressure. The recovered crude oil product was purified by chromatography on silica gel eluted with 5% ethyl acetate in hexane to provide 1.5 g (71%) of 6-(carbethoxymethyl)-3-phenylcyclohexanone.

1. customfor 41 hours
2. filtrationThe mixture was filtered through celite
3. customthe solvent was removed under reduced pressure
4. customThe recovered crude oil product
5. customwas purified by chromatography on silica gel
6. washeluted with 5% ethyl acetate in hexane