Hydrochloric Acid → HCID 54018450, compound

HRID 1196492Notes

Reaction equation

[C:1](O)(=O)[C:2](O)=O.[CH2:7]([O:11][C:12](=[O:27])[CH2:13][C:14]1[C:15]([NH2:26])=[N:16][NH:17][C:18]=1[C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=1)[CH2:8]CC.Cl.O.[CH2:30](O)C>>[CH2:7]([O:11][C:12](=[O:27])[CH2:13][C:14]1[C:18]([C:19]2[CH:20]=[CH:21][C:22]([Cl:25])=[CH:23][CH:24]=2)=[N:17][N:16]2[CH:2]=[CH:1][CH:30]=[N:26][C:15]=12)[CH3:8]

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 962Water

HCID 86745840HCID 86745840, compound

Product 1

HCID 54018450HCID 54018450, compound

Procedure

A suspension of 23.0 g (0.057 mole) of 3-amino-5-(4-chlorophenyl)-1H-pyrazole-4-acetic acid butyl ester ethanedioate and 9.6 g (0.057 mole) of malonaldehyde bis(dimethylacetal) (99%) in 250 ml of absolute ethanol was treated with 5 ml of concentrated hydrochloric acid and 10 ml of water.

Sources & evidence

ORD record: ord-0fc48940a8d64a5aa6eb05f205217376
Source dataset: uspto-grants-1992_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05114944

Reaction notes

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