HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Methyl 8-(phenylmethyl) 1,4-dioxa-8-azaspiro[4.5]decane-7,8-dicarboxylate → Methyl 1,4-dioxa-8-azaspiro[4.5]decane-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Methyl 8-(phenylmethyl) 1,4-dioxa-8-azaspiro[4.5]decane-7,8-dicarboxylate | HCID 15123244 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 1,4-dioxa-8-azaspiro[4.5]decane-7-carboxylate | HCID 15123245 | 90.9% |
Reaction Steps
A solution of the product of stage (iii) (5.50 g) in ethyl acetate (60 ml) was hydrogenated over 10% palladium on carbon (0.50 g) for 4 h. The catalyst was filtered off and the filtrate evaporated in vacuo to give the title compound as an oil (3.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05114945 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-df3bab4c001e4d309861dc12845f9a9e |
| Source note | uspto-grants-1992_05 |