Potassium Bromide → HCID 19899207, compound

HRID 1196635Notes

Reaction equation

HRID 1196635 reaction equation
[ClH:1].[NH2:2][CH2:3][CH2:4][CH:5]1[CH2:9][C:8]2[C:10]([CH3:24])=[C:11]([O:16]CC3C=CC=CC=3)[C:12]([CH3:15])=[C:13]([CH3:14])[C:7]=2[O:6]1.[K+].[Br-]>>[ClH:1].[NH2:2][CH2:3][CH2:4][CH:5]1[CH2:9][C:8]2[C:10]([CH3:24])=[C:11]([OH:16])[C:12]([CH3:15])=[C:13]([CH3:14])[C:7]=2[O:6]1

Participants

3

Reactant 2

HCID 253877Potassium BromideHCID 19899202HCID 19899202, compound

Product 1

HCID 19899207HCID 19899207, compound

Procedure

The de-benzylization of the 2-(RS)-(2-aminoethyl)-2,3-dihydro-5-benzyloxy-4,6,7-trimethylbenzofurane hydrochloride is done with the same process as described in example 15. A white solid is obtained. m.p. 198°-199° C.; IR (KBr): 3410 (νOH), 3059 cm-1 (νNH3 +); 1H-NMR (D2O): δ3.4-2.7 (4H,m), 2.3-2.1 (2H,m), 2.1 (6H,s), 2.0 (3H,s).

Workup

  1. customA white solid is obtained

Sources & evidence

ORD record
ord-084e9d25460c40a996304d70114892d3
Source dataset
uspto-grants-1992_05
Patent number
US05114966

Reaction notes

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