Potassium Bromide → HCID 21659422, compound

HRID 1196636Notes

Reaction equation

[CH2:1]([CH:3]1[CH2:7][C:6]2[C:8]([CH3:22])=[C:9]([O:14]CC3C=CC=CC=3)[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]=2[O:4]1)[CH3:2].[K+].[Br-]>>[CH2:1]([CH:3]1[CH2:7][C:6]2[C:8]([CH3:22])=[C:9]([OH:14])[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]=2[O:4]1)[CH3:2]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 19899197HCID 19899197, compound

Product 1

HCID 21659422HCID 21659422, compound

Procedure

The de-benzylization of the 2-(RS)-ethyl-2,3-dihydro-5-benzyloxy-4,6,7-trimethylbenzofurane is done by following the procedure given in example 15. A white solid is obtained. m.p. 73°-75° C.; IR (KBr): 3378 cm-1 (νOH); 1H-NMR (CDCl3): δ4.9-4.5 (1H,m), 4.2 (1H,s), 3.3-2.7 (2H,m), 2.1 (6H,s), 2.0 (3H,s), 1.8- 1.5 (2H,m), 1.1 (3H,t).

Workup

customA white solid is obtained

Sources & evidence

ORD record: ord-3717bb1f21b5403aa41dc5218fdf5212
Source dataset: uspto-grants-1992_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05114966

Reaction notes

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