HCID 67896149, compound → HCID 19899009, compound

HRID 1196658Notes

Reaction equation

HRID 1196658 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]3[CH2:13][C:14](C(O)=O)([C:17]([OH:19])=[O:18])[CH2:15][CH2:16][C:11]=3[O:10][N:9]=2)=[CH:4][CH:3]=1>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]3[CH2:13][CH:14]([C:17]([OH:19])=[O:18])[CH2:15][CH2:16][C:11]=3[O:10][N:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 67896149HCID 67896149, compound

Product 1

HCID 19899009HCID 19899009, compoundYield 77.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1 g of 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,2-benzisoxazole-5,5-dicarboxylic acid was heated to 200°-210° C. for 5 minutes until effervescence had ceased. The residue was dissolved in ethanol and there was obtained from the solution 0.67 g of 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,2-benzisoxazole-5-carboxylic acid of melting point 203°-205° C.

Sources & evidence

ORD record
ord-76fc11d8131347aab3fe8237fc074d40
Source dataset
uspto-grants-1992_05
Patent number
US05114960

Reaction notes

Loading…