Triphenylphosphine → HCID 19898753, compound

Participants

Reaction Steps

The same procedure as in Example 8-(2) was effected so as to react and treat 0.6 g of N-ethyl-N-(2-hydroxyethyl)-N'[1,3-dimethyl-2,4-dioxopyrimidine-6-yl]ethylenediamine (Compound 32), 0.57 g of 2-ethoxycarbonyl-7-hydroxy-4-oxo-4H-1-benzopyran (Compound 33), 30 ml of tetrahydrofuran containing 0.77 g of triphenylphosphine and 0.47 ml of diethyl azodicarboxylate, thereby obtaining 0.81 g (yield 69%) of oily 1,3-dimethyl-6-(2-[N-ethyl-N-[2-(2-ethoxycarbonyl-4-oxo-4H-1-benzopyran-7-yl)oxyethyl]amino]ethylamino)-2,4(1H,3H)-pyrimidinedione (the non-oxalate of Compound 34).

Provenance & Evidence