Ethyl orthoformate → 2,3-Dibromopropionaldehydediethylacetal

HRID 1196742Notes

Reaction equation

HRID 1196742 reaction equation
[Br:1][C:2](=O)[CH:3]([Br:5])C.C(O[CH:10]([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13])C>C(O)C>[CH2:15]([O:14][CH:10]([O:11][CH2:12][CH3:13])[CH:3]([Br:5])[CH2:2][Br:1])[CH3:16]

Participants

4

Reactant 2

HCID 31214Ethyl orthoformateHCID 79047Propanoyl bromide, 2-bromo-

Product 1

HCID 42635672,3-Dibromopropionaldehydediethylacetal

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7 g of 1,2-dibromo-propionaldehyde are added to a mixture of 5 g of ortho-formic acid triethyl-ester and 10 ml of ethanol. The solution is refluxed for 2 hours, remains standing for a night, then it is vacuum-distilled.

Workup

  1. temperatureThe solution is refluxed for 2 hours
  2. waitremains standing for a night
  3. distillationit is vacuum-distilled

Sources & evidence

ORD record
ord-0d0a8735052f407fb6e773a75694f006
Source dataset
uspto-grants-1992_05
Patent number
US05116402

Reaction notes

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