Water → 4,5-Dihydro-3-(3-methyl-5-isoxazolyl)-4-oxo-imidazo[1,5-a]quinoxaline

HRID 1196861Notes

Reaction equation

HRID 1196861 reaction equation
C([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:8]2[CH:15]=[N:16][C:17]([C:18]3[O:22][N:21]=[C:20]([CH3:23])[CH:19]=3)=[C:7]2[C:6]1=[O:24])(C)(C)C.O>C(O)C.Cl>[CH3:23][C:20]1[CH:19]=[C:18]([C:17]2[N:16]=[CH:15][N:8]3[C:9]4[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=4)[NH:5][C:6](=[O:24])[C:7]=23)[O:22][N:21]=1

Participants

5

Reactant 2

HCID 962WaterHCID 19896721HCID 19896721, compound

Product 1

HCID 198967194,5-Dihydro-3-(3-methyl-5-isoxazolyl)-4-oxo-imidazo[1,5-a]quinoxaline

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Procedure

A stirred suspension of 5-tert-butyl-4,5-dihydro-3-(3methyl-5isoxazolyl)-4oxo-imidazo[1,5-a]quinoxaline (0.65 g) in a mixture of ethanol (10 ml) and 4 M hydrochloric acid (1 ml) was refluxed for 10 min. Then the mixture was cooled to room temperature and water (10 ml) was added. The precipitated product was collected by filtration and dried to give the title compound as a white solid, m.p. 393° C. (Compound 18).

Workup

  1. temperaturewas refluxed for 10 min
  2. filtrationThe precipitated product was collected by filtration
  3. customdried

Sources & evidence

ORD record
ord-37b856f0b0f94e709cb14c438be35b7c
Source dataset
uspto-grants-1992_05
Patent number
US05116841

Reaction notes

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