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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1196939Generated: October 31, 2026

Methyl iodide → 1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-one

https://huagongshe.com/reaction/1196939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant1-(2,4-Difluorophenyl)-2-(3-pyridinyl)-ethanoneHCID 18956524—
Product1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-oneHCID 1895654173.6%

Reaction Steps

Methylation of the product of part (i) (5.0 g) with iodomethane (7.60 g) according to the method of Example 11(ii) gave the title compound as an oil (3.90 g) which was used directly in the next stage.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05116844
Source datasetuspto-grants-1992_05
ORD IDord-e3fe0713b35d4230a8b3914976606637
Source noteuspto-grants-1992_05