Hydrochloric Acid → HCID 178440822, compound

HRID 1196965Notes

Reaction equation

HRID 1196965 reaction equation
[O:1]=[C:2]1[CH:6]=[SH:5](=[C:7]([CH3:23])[CH:8]=[CH:9][C:10]2[CH:22]=[CH:21][CH:20]=[CH:19][C:11]=2[O:12][CH2:13][C:14]([O:16]CC)=[O:15])[C:4](=[S:24])[NH:3]1.[OH-].[Na+].Cl>O>[O:1]=[C:2]1[CH:6]=[SH:5](=[C:7]([CH3:23])[CH:8]=[CH:9][C:10]2[CH:22]=[CH:21][CH:20]=[CH:19][C:11]=2[O:12][CH2:13][C:14]([OH:16])=[O:15])[C:4](=[S:24])[NH:3]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178472963HCID 178472963, compound

Product 1

HCID 178440822HCID 178440822, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 0.85 g of ethyl 2-[3-(4-oxo-2-thioxo-5-thiazolinylidene)-1-butenyl]phenoxyacetate, 5 ml of water and 1 ml of 5% sodium hydroxide solution was stirred at room temperature for one hour. 10% hydrochloric acid was added to the mixture and the precipitated crystals were collected by filtration and washed with methanol to give 2-[3-(4-oxo-2thioxo-5-thiazolinylidene)-1-butenyl]phenoxyacetic acid in the yield of 76%.

Workup

  1. filtrationthe precipitated crystals were collected by filtration
  2. washwashed with methanol

Sources & evidence

ORD record
ord-939dd6ec042045239f24e06e44947ea5
Source dataset
uspto-grants-1992_05
Patent number
US05116855

Reaction notes

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