Sodium Bicarbonate → HCID 60865, compound

HRID 1196995Notes

Reaction equation

HRID 1196995 reaction equation
[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][CH:5]=[C:6]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[CH2:10][O:9][C:8]2[CH:17]=[CH:18][C:19]([CH2:21][CH2:22][OH:23])=[CH:20][C:7]1=2.CC(C)=[O:27].OS(O)(=O)=O.O=[Cr](=O)=O.C(=O)(O)[O-].[Na+]>CC(C)=O>[CH3:24][N:2]([CH3:1])[CH2:3][CH2:4][CH:5]=[C:6]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[CH2:10][O:9][C:8]2[CH:17]=[CH:18][C:19]([CH2:21][C:22]([OH:27])=[O:23])=[CH:20][C:7]1=2

Participants

5

Reactant 3

HCID 516892Sodium BicarbonateHCID 54552025HCID 54552025, compoundHCID 131709961Jones' reagent

Product 1

HCID 60865HCID 60865, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In this Example, 2.2 g of 11-(3-dimethylaminopropylidene)-2-(2-hydroxyethyl)-6,11-dihydrodibenz[b,e]oxepin is dissolved in 100 ml of acetone. The Jones reagent is added to the solution until the reaction solution shows an orange color and the mixture is stirred at room temperature for one hour. Sodium bicarbonate is added thereto and an inorganic substance is removed by filtration. The solvent of the filtrate is distilled away under reduced pressure to obtain the desired product. The physicochemical properties of the product coincide with those of the product obtained in Example 35.

Workup

  1. customan inorganic substance is removed by filtration
  2. distillationThe solvent of the filtrate is distilled away under reduced pressure

Sources & evidence

ORD record
ord-5508f2c139a04bcc89d0085b709f9241
Source dataset
uspto-grants-1992_05
Patent number
US05116863

Reaction notes

Loading…