Hexane → HCID 14459226, compound

Participants

Reaction Steps

0.21 Gram of 5-chloro-2-fluoro-4-[2-chloro-4-(trifluoromethyl)phenylthio]aniline was dissolved in 6 ml of toluene, and to this solution was added dropwise a solution of 0.11 g of 2,6-difluorobenzoyl isocyanate in 4 ml of toluene with ice-cooling and stirring. After completion of addition, the reaction solution was stirred overnight at room temperature. Thereafter, 6 ml of n-hexane was added, the precipitated crystals were filtered off and dried to obtain 0.20 g of N-(2,6-difluorobenzoyl)-N'-[5-chloro-2-fluoro-4-{2-chloro-4-(trifluoromethyl)phenylthio}phenyl]urea as white crystals.

Provenance & Evidence