Hydrochloric Acid → HCID 178512899, compound

Participants

Reaction Steps

After 125.7 g (0.25 mol) of BOC-Gly-Arg-CHA.HCl was dissolved in a small amount of MeOH, 500 ml (0.10 mol) of 2N HCl/AcOH was added to the solution. The mixture was reacted at room temperature for an hour with stirring. After completion of the reaction, the reaction mixture was reprecipitated in 4.5 liters of ether. The precipitated crystals were taken by filtration and dried to give 109.8 g (100%) of H-Gly-Arg-CHA.2HCl.

Provenance & Evidence