Glycidol → HCID 22138552, compound

HRID 1197154Notes

Reaction equation

HRID 1197154 reaction equation
[CH2:1]1[O:3][CH:2]1[CH2:4][OH:5].[CH3:6][NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>C1(C)C=CC=CC=1>[CH3:6][N:7]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:1][CH:2]([OH:3])[CH2:4][OH:5]

Participants

4

Reactant 2

HCID 11164GlycidolHCID 75539N-Methyloctadecylamine

Product 1

HCID 22138552HCID 22138552, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of glycidol (4 ml, 60 mmol) and N-methyl-octadecylamine (16 g, 60 mmol) in dry toluene (50 ml) was refluxed under stirring for 3 hours. After evaporation of the solvent, the residue was crystallized to yield 16 g (84%) of the title compound. m.p. 59° C. (Hexane).

Workup

  1. temperaturewas refluxed
  2. customAfter evaporation of the solvent
  3. customthe residue was crystallized

Sources & evidence

ORD record
ord-e0b597862f6d485f909f3d94728ab293
Source dataset
uspto-grants-1992_05
Patent number
US05116992

Reaction notes

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