反应详情

To a solution of 3-butyn-1-ol (g) (10.0 g) in DMF (80 ml) were added t-butyldimethylsilyl chloride (21.5 g) and imidazol (10.6 g), and the resultant mixture was kept at 35° C. for 7 hours. The reaction mixture was treated in the conventional manner and the obtained crude produce was distilled to give the title compound (h). Yield: 17.4 g (66%)

1. additionThe reaction mixture was treated in the conventional manner
2. customthe obtained crude
3. customproduce
4. distillationwas distilled