HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19107104, compound → HCID 19107020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19107104 | HCID 19107104 | — |
| Reactant | Potassium trimethylsilanolate | HCID 23668039 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19107020 | HCID 19107020 | 78% |
Reaction Steps
A solution of the compound from Example 51 (1.5 g, 5.8 mmol) and potassium trimethylsilanolate (1.5 g, 11.6 mmol) in 25 ml THF was refluxed 60 hours. Workup as before and chromatography on silica gel gave the title compound (1.1 g, 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05276053 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-5027bedf73bf4e1bb8d755ac76aa0b37 |
| Source note | uspto-grants-1994_01 |