1,4-Dioxane → HCID 19106991, compound

HRID 1197545Notes

Reaction equation

HRID 1197545 reaction equation
[S:1]1[CH2:6][CH:5]=[C:4](N2CCCC2)[CH2:3][CH2:2]1.[Br:12][C:13]1[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15]Br.[O:21]1CCOCC1>>[Br:12][C:13]1[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15][CH:5]1[C:4](=[O:21])[CH2:3][CH2:2][S:1][CH2:6]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 769652-Bromobenzyl bromideHCID 132874681-(3,6-Dihydro-2H-thiopyran-4-yl)pyrrolidine

Product 1

HCID 19106991HCID 19106991, compoundYield 15%

Procedure

In a manner similar to that described in Example 82, 1-(3,6-dihydro-2H-thiopyran-4-yl)pyrrolidine (25.0 g, 0.15 mole) or as is in dioxane (100 ml) was treated with 2-bromobenzyl bromide (40.0 g, 0.16 mol) to give the title compound as a clear oil (16.3 g, 15%).

Sources & evidence

ORD record
ord-8bbf473c2f2445c982a19874342cf0a9
Source dataset
uspto-grants-1994_01
Patent number
US05276053

Reaction notes

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