Trifluoroacetic acid → HCID 54392866, compound

HRID 1197571Notes

Reaction equation

HRID 1197571 reaction equation
C(OC([NH:8][C:9]1([C:12]2[CH:17]=[CH:16][C:15]([N:18]3[CH2:22][CH2:21][N:20]([C:23]4[CH:28]=[CH:27][C:26]([CH2:29][CH2:30][C:31]([O:33][CH3:34])=[O:32])=[CH:25][CH:24]=4)[C:19]3=[O:35])=[CH:14][CH:13]=2)[CH2:11][CH2:10]1)=O)(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[NH2:8][C:9]1([C:12]2[CH:13]=[CH:14][C:15]([N:18]3[CH2:22][CH2:21][N:20]([C:23]4[CH:28]=[CH:27][C:26]([CH2:29][CH2:30][C:31]([O:33][CH3:34])=[O:32])=[CH:25][CH:24]=4)[C:19]3=[O:35])=[CH:16][CH:17]=2)[CH2:10][CH2:11]1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 22098861HCID 22098861, compound

Product 1

HCID 54392866HCID 54392866, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from 1-[4-(1-tert.butyloxycarbonylaminocyclopropyl)-phenyl]-3-[4-(2-methoxycarbonyl-ethyl)-phenyl]-imidazolidin-2-one by stirring for two hours in a 1:1 mixture of methylene chloride and trifluoroacetic acid.

Sources & evidence

ORD record
ord-6e8ef36bd6f54515b05890b5e99f358b
Source dataset
uspto-grants-1994_01
Patent number
US05276049

Reaction notes

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