反应详情

温度

200 °C

To a 250-ml three-necked flask equipped with a thermometer, stirrer, condenser and nitrogen inlet were charged 66 g. of nonylphenol and 30 g. of 2-methyl-2-oxazoline. The mixture was heated to 200° C. for six hours. About 80 g. of 85% phosphoric acid and 20 g. of water were then added. The mixture was heated to reflux for eight hours. The resulting reaction mixture was neutralized with sodium hydroxide solution. The resulting product was washed with water and then dried. 2-Nonylphenoxyethanamine was obtained in quantitative yield and the product purity by NMR spectroscopy analysis was found to be about 98%.

1. customTo a 250-ml three-necked flask equipped with a thermometer, stirrer, condenser and nitrogen inlet
2. additionwere charged 66 g
3. temperatureThe mixture was heated
4. temperatureto reflux for eight hours
5. customThe resulting reaction mixture
6. washThe resulting product was washed with water
7. customdried