Hydrochloric Acid → HCID 178502022, compound

Participants

Reaction Steps

Methyl (±)-[5-(aminophenylmethyl)-1H-benzimidazol-2-yl]carbamate (1 g) was suspended in water (5 mL). To this mixture was added aqueous HCl (12N) with stirring to adjust the pH to ph ~2. As stirring was continued the hydrochloride salt precipitated from the solution. The mixture was cooled in an ice bath and the title product as a precipitate was collected by filtration, m.p.>300° C. Yield: 1.05 g (ca. 85%).

Provenance & Evidence