Propionylhydrazine → HCID 19105237, compound

HRID 1197871Notes

Reaction equation

HRID 1197871 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]=[C:10](Cl)[C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)=[CH:5][CH:4]=1.[C:21]([NH:25][NH2:26])(=O)[CH2:22][CH3:23]>C1(C)C=CC=CC=1.C(N(CC)CC)C>[CH2:22]([C:21]1[N:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)=[N:26][N:25]=1)[CH3:23]

Participants

5

Reactant 2

HCID 79890PropionylhydrazineHCID 13432839HCID 13432839, compound

Product 1

HCID 19105237HCID 19105237, compoundYield 56.8%

Reagents, catalysts & solvents 2

HCID 1140TolueneSolventHCID 8471TriethylamineSolvent

Procedure

Using the procedure of Step B of Example 4, 15 g of the product of Step A and 8.8 g of propionic acid hydrazide in 200 ml of toluene and 14 ml of triethylamine were reacted to obtain 9.5 g of 3-ethyl-4-(4-methoxyphenyl)-5-(3-nitrophenyl)-4H-1,2,4-triazole melting at 126° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-23dd460ee46a42bc92ed25eed5873674
Source dataset
uspto-grants-1994_01
Patent number
US05278180

Reaction notes

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