Piperidin-4-ol → HCID 18959737, compound
Reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][C:12]2[O:17][C:16]([CH:18]3[CH2:22][CH2:21][CH2:20][CH2:19]3)=[CH:15][C:14](=[O:23])[C:13]=2[CH:24]=1.[OH:25][CH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[ClH:1].[CH:18]1([C:16]2[O:17][C:12]3[CH:11]=[CH:10][C:9]([O:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][N:29]4[CH2:30][CH2:31][CH:26]([OH:25])[CH2:27][CH2:28]4)=[CH:24][C:13]=3[C:14](=[O:23])[CH:15]=2)[CH2:22][CH2:21][CH2:20][CH2:19]1Participants
3
Procedure
The reaction between 6-(6-chlorohexoxy)-2-cyclopentyl-4H-1-benzopyran-4-one and 4-hydroxypiperidine was carried out in a manner similar to that of Example 3: mp 125°-126° C.
Sources & evidence
- ORD record
- ord-cd55237cfc394e6899268adf0d8c3f0c
- Source dataset
- uspto-grants-1994_01
- Patent number
- US05278174
Reaction notes
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