Piperidin-4-ol → HCID 14982993, compound

HRID 1197968Notes

Reaction equation

HRID 1197968 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:18])[CH:7]=[C:8]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[O:9]2)=[CH:4][CH:3]=1.Br[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]Cl.[OH:26][CH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[OH:26][CH:27]1[CH2:32][CH2:31][N:30]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:1][C:2]2[CH:3]=[CH:4][C:5]3[C:6](=[O:18])[CH:7]=[C:8]([C:12]4[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=4)[O:9][C:10]=3[CH:11]=2)[CH2:29][CH2:28]1

Participants

4

Reactant 3

HCID 79341Piperidin-4-olHCID 960701-Bromo-5-chloropentaneHCID 52818947-Hydroxyflavone

Product 1

HCID 14982993HCID 14982993, compound

Procedure

The compound was prepared by a method similar to Example 3 from 7-hydroxyflavone, 1-bromo-5-chloropentane, and 4-hydroxypiperidine: mp 94°-95° C.

Sources & evidence

ORD record
ord-11a92ed1d44e493582e9e28252d4c56c
Source dataset
uspto-grants-1994_01
Patent number
US05278174

Reaction notes

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