反应详情

Alternatively, the reaction for the selective methylation can be carried out by reacting a mixture of (6-methoxy-2-naphthyl)acetic acid, dimethyl carbonate and K2CO3, in the 1:20:2 molar ratio, in autoclave at a temperature of 220° C. The reaction is completed within about 8 hours. (In this case DMC acts first as a methylating agent for the carboxylic group, through an already known reaction; then the monomethylation reaction takes place on the resulting ester).

1. customAlternatively, the reaction for the selective methylation
2. customat a temperature of 220° C
3. custom(In this case DMC acts first as a methylating agent for the carboxylic group, through an already known reaction
4. customthen the monomethylation reaction