Sulfuric Acid → 4-(3,4-Dimethoxyphenyl)-6-methyl-1,2,3,4-tetrahydroisoquinoline

HRID 119802Notes

Reaction equation

HRID 119802 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][CH2:8][CH:9]([c:10]2[cH:11][c:12]([O:18][CH3:19])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[OH:20])[cH:21][cH:22]1.[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34].[S:23](=[O:24])(=[O:25])([OH:26])[OH:27]>>[CH3:1][c:2]1[cH:3][cH:4][c:5]2[c:21]([cH:22]1)[CH:9]([c:10]1[cH:11][c:12]([O:18][CH3:19])[c:13]([O:16][CH3:17])[cH:14][cH:15]1)[CH2:8][NH:7][CH2:6]2

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 6422Trifluoroacetic acidHCID 10590414alpha-[[(4-Methylbenzyl)amino]methyl]-3,4-dimethoxybenzyl alcohol

Product 1

HCID 106843994-(3,4-Dimethoxyphenyl)-6-methyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-5776ae0963d248ffa631532df8d9a79d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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