Triethylamine → HCID 14969216, compound

HRID 1198040Notes

Reaction equation

HRID 1198040 reaction equation
[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=O.[Cl-].[Mg+2].[Cl-].C(O)(=O)[CH2:26][C:27]([OH:29])=[O:28].[CH2:32]([K])[CH3:33].C(N(CC)CC)C>>[CH2:32]([O:29][C:27](=[O:28])[CH2:26][C:19](=[O:21])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][O:7][CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6][O:1]1)[CH3:33]

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 5360315Magnesium ChlorideHCID 14405876HCID 14405876, compoundHCID 178461627HCID 178461627, compound

Product 1

HCID 14969216HCID 14969216, compound

Procedure

The title compound was prepared from 12-[(tetrahydro-2H-pyran-2-yl)oxy]-dodecanoic acid (10.0 g, 0.033 mol), 1,11-carbonyldiimidazole (6.47 g, 0.039 mol), magnesium chloride (6.02 g, 0.063 mol), ethyl potassium malonate (9.06 g, 0.053 mol), and triethylamine (7.40 g, 0.073 mol) using the procedure described in Example 3, Step A.

Sources & evidence

ORD record
ord-261f53b7233a4b4ea50699ea81e617d0
Source dataset
uspto-grants-1994_01
Patent number
US05278326

Reaction notes

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