HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 6-(Dodecylsulfonyl)-3-oxo-hexanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Magnesium Chloride | HCID 5360315 | — |
| Reactant | Butanoic acid, 4-(dodecylsulfonyl)- | HCID 11001756 | — |
| Reactant | HCID 178461627 | HCID 178461627 | — |
| Product | 6-(Dodecylsulfonyl)-3-oxo-hexanoic acid ethyl ester | HCID 53911555 | — |
Reaction Steps
The title compound was prepared from 4-(dodecylsulfonyl)butanoic acid (H. Gilman, et al, J. Am Chem. Soc. 74, 4452 (1952)) (2.50 g, 0.07 mol), 1,1'carbonyldiimidazole (1.50 g, 0.09 mol), magnesium chloride (1.41 g, 0.014 mol), ethyl potassium malonate (2.12 g, 0.012 mol), and triethylamine (1.73 g, 0.017 mol) using the procedure described in Example 3, Step A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05278326 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-213fb1421ede44b9ae9770a2f7f4ac65 |
| Source note | uspto-grants-1994_01 |