HCID 131718312, compound → HCID 131718311, compound

Participants

Reaction Steps

5-Phenoxypentylaminomethylenebisphosphonic acid disodium salt trihydrate (1.0 g) was dissolved in water (5 ml). The solution was processed with a column of CG-50 (H type, 32 ml). The solid matter obtained from the acidic portion eluted with water was recrystallized from water-methanol to afford 5-phenoxypentylaminomethylenebisphosphonic acid monosodium salt hemihydrate (0.58 g, 68%) as colourless prisms, m.p.>300° C.

Provenance & Evidence