Sodium Hydroxide → HCID 18982861, compound

HRID 1198128Notes

Reaction equation

HRID 1198128 reaction equation
C([O:4][CH:5]([C:7]1[N:12]=[CH:11][N:10]=[C:9]([Cl:13])[C:8]=1[Cl:14])[CH3:6])(=O)C.[OH-].[Na+]>O1CCCC1>[Cl:13][C:9]1[C:8]([Cl:14])=[C:7]([CH:5]([OH:4])[CH3:6])[N:12]=[CH:11][N:10]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22097406HCID 22097406, compound

Product 1

HCID 18982861HCID 18982861, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In 50 ml of tetrahydrofuran was dissolved 4.0 g of 6-(1-acetoxyethyl)-4,5-dichloropyrimidine, and to the mixture was slowly added dropwise 30 ml of an 1N-sodium hydroxide aqueous solution under stirring. After the dropwise addition, the mixture was further stirred for 1 hour at room temperature to complete the reaction.

Workup

  1. additionAfter the dropwise addition
  2. stirringthe mixture was further stirred for 1 hour at room temperature
  3. customthe reaction

Sources & evidence

ORD record
ord-ee82a66cc18c43d09a06f7d427a37ec5
Source dataset
uspto-grants-1994_01
Patent number
US05280025

Reaction notes

Loading…