HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalate → HCID 86744899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalate | HCID 71081 | — |
| Reactant | HCID 86744900 | HCID 86744900 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86744899 | HCID 86744899 | 74% |
Reaction Steps
3.8 g. (18 mmole) 2-Azido-2-methylpropionic acid 4-hydroxypiperidide are dissolved in 10 ml. methanol and hydrogenated over Raney nickel at ambient temperature and 1 bar hydrogen pressure. After filtering off with suction and evaporation of the filtrate, the residue is reacted in ethanol with oxalic acid. There are obtained 3.0 g. of the oxalate of the title compound; m.p. 197° C. Yield 74% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05280031 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-5b9bdb660f894abf9790c42979aa5fa2 |
| Source note | uspto-grants-1994_01 |