HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1198288Generated: October 30, 2026
Dimethylamine → 2-Amino-4-dimethylamino-6-trifluoromethoxy-1,3,5-triazine
https://huagongshe.com/reaction/1198288
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-Amino-4-fluoro-6-trifluoromethoxy-1,3,5-triazin | HCID 15010388 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Amino-4-dimethylamino-6-trifluoromethoxy-1,3,5-triazine | HCID 15010399 | — |
Reaction Steps
5.0 g (0.111 mol) of dimethylamine were passed over the course of 20 minutes into a stirred solution of 11 g (0.055 mol) of 2-amino-4-fluoro-6-trifluoromethoxy-1,3,5-triazine in 150 ml of tetrahydrofuran at 0° C. The mixture was stirred at 0° C. for one hour and at 22° C. overnight. Concentration, washing with water and drying yielded 9.9 g (80.7% of theory) of the title compound of melting point 114°-118° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05280118 |
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| Source dataset | uspto-grants-1994_01 |
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| ORD ID | ord-677b97ff6545471694672c1b17f2e501 |
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| Source note | uspto-grants-1994_01 |
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