Hydrochloric Acid → HCID 19103760, compound

Participants

Reaction Steps

A solution of 0.2 mol of n-butyllithium in 65 ml of hexane is added to a mixture of 0.1 mol of 1,2-difluorobenzene, 0.2 mol of potassium tert.-butylate and 100 ml of tetrahydrofuran at -100° C. After the mixture has been stirred for 10 minutes, a mixture of 0.2 mol of 4-propylcyclohexanone and 20 ml of tetrahydrofuran is added at -90° C. After the mixture has been stirred at -40° C. for 2 hours, it is warmed to room temperature and 30 ml of 2 normal hydrochloric acid solution are added. Heating for 2 hours and customary working up give 1,4-bis-(4-propylcyclohex-1-enyl)-2,3-difluorobenzene, C 59° N 120° I.

Provenance & Evidence