Tetrahydrofuran → (4,5-Dihydro-oxazol-2-yl)-[2-(4-fluoro-phenyl)-1-phenyl-ethyl]-amine

HRID 119846Notes

Reaction equation

HRID 119846 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[Cl:17][CH2:18][CH2:19][N:20]=[C:21]=[O:22].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[NH2:16])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[NH:16][C:21]2=[N:20][CH2:19][CH2:18][O:22]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 160352-Chloroethyl isocyanateHCID 150089772-(4-Fluorophenyl)-1-phenylethan-1-amine

Product 1

HCID 68699396(4,5-Dihydro-oxazol-2-yl)-[2-(4-fluoro-phenyl)-1-phenyl-ethyl]-amine

Sources & evidence

ORD record
ord-5042d373eb694fd994e2d25923603c0b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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