反应详情

Wet Raney nickel was added in portions to a stirred refluxing solution of 7-(benzyloxy)-3-(methylthio)indole (4.0 g, 14.9 mmol) in ethyl acetate (100 ml) and ethanol (60 ml) until all the starting material had been consumed (by RP HPLC). The mixture was filtered, the filtrate evaporated and the residue chromatographed on silica in ethyl acetate-hexane (1:8) to give a pale oil.

1. customhad been consumed (by RP HPLC)
2. filtrationThe mixture was filtered
3. customthe filtrate evaporated
4. customthe residue chromatographed on silica in ethyl acetate-hexane (1:8)
5. customto give a pale oil