HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzaldehyde | HCID 10017305 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol | HCID 10827738 | — |
Reaction Steps
Solid sodium borohydride (2.5 g) was added in portions to a stirred suspension of crude 3-[2(E)-(7-chloroquinolin-2-yl)ethenyl]benzaldehyde (5.8 g) in methanol (200 ml). The mixture was filtered and the filtrate was concentrated to ca 70 ml and diluted with hot water to give crystals, m.p. 141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05281593 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-79408cb9ec7d4ae1be7b3f1d54a7a93c |
| Source note | uspto-grants-1994_01 |